ORGAN WEIGHTS

Organ Weights were entered on the gross pathology sheets at the time of autopsy.  We compared all of the individual organ weights on appendix table 5 in the submission to FDA (Vol 1, pp. 222-226) with the original data on the gross pathology sheets.  A total of eleven (11) errors were noted in transcribing the raw data from the pathology sheets, to the tables in the submission to FDA.

The errors are tabulated below:

Animal No.

Organ

Wt. Shown in Submission

Wt. Recorded on Original Pathology Sheet

A12CM

Kidneys

3.75 G

3.45 G

L28LM

Ven. Prostrate

747 mg.

474.7 mg.

C01HM

Kidneys

9.40 G

9.219 G

C02HM

Kidneys

1.46 G

4.259 G

E14HM

Kidneys

11.74 G

4.746 G

J12HM

Pituitary

3.0 mg

3.3 mg

J30HM

Ven. Prostrate

444 mg.

444.8 mg

F17CF

Ovaries

36.7 mg.

233.5 & 36.7 mg

H30CF

Liver

9.4 G

9.493 G

B20HF

Uterus

1115 mg.

1155 mg.

K11HF

Adrenals

799.1 mg

797.1 mg.

Copies of the applicable pages of the submission, appendix table 5, with errors indicated, are attached along with copies of the gross pathology sheets documenting the errors. (See exhibit #83)