|
The
Good Stuff
Dr.
Monte cautioned in 1987 that he didn't want to sound like a "conspiracy
theory" hound, but the aspartame chronology clarifies its commercial emergence.
The FDA Board of Inquiry advised against the sweetener on September 30,
1980. On January21, 1981-the day after Reagan's inauguration-Searle submitted
"ten new studies." Dr. Monte was skeptical. "It is impossib1e that they
could have conducted those studies in four months," he said. "Obviously
they'd previously done those studies but hadn't officially submitted them,
although much of the information in those studies was informally presented
to the board of inquiry." With the "new tests" in hand, Hayes acted as
though critical, overriding evi dence had proven the safety of aspartame.82
James
Turner, representing thc Community Nutrition Institute in Washington, D.C.,
said that Arthur Hull Hayes, to arrive at his decision that aspartame is
safe, firewalked apath "through a mass of scientific mismanagement, improper
procedures, wrong conclusions and general scientific inexactness." Two
FDA officials declared in 1985 that Hayes was determined to clear all obstacles
to NutraSweet approval. One FDA bureaucrat reported that "people at the
top" were closed to questions concerning the quality of the tests submitted
by Searle.83
In
July, 1984 a broad investigation of NutraSweet's adverse effects was conducted
by the FDA and the Centers for Disease Control. Federal health officials
said at the outset that they believed no harm would emerge from the data
to indict aspartame. Robert McQuate, Ph.D., science director of the National
Soft Drink Association, predicted with mystical confidence that the study
would "provide further evidence that aspartame is a safe ingredient."84
Dr.
McQuate didn't fret the goring of his biochemical ox. In November the CDC
announced that no "serious, widespread" side effects had been found.85
It was "unlikely," said CDC officials, that "complainers" could establish
a link between NutraSweet and their maladies-the same bromide once tossed
to victims of radiation experiments. The reported side-effects of aspartame
fell into two distinct categories: central nervous system (65%) and gastrointestinal
disorders (24%).86 Yet the CDC claimed erroneously that no consistent reaction
pattern had been found. 87 Robert Shapiro, then president of Nutrasweet,
used the occasion to enthuse that the survey "clearly established the safety"
of the sugar substitute.88 Nevertheless, the CDC recommended a new set
of studies because aspartame users continued to complain of ill effects.
Based
on the ersatz assurances of the CDC report, PepsiCo announced that it would
drop saccharine and begin sweetening its diet drinks entirely with aspartame.
The decision would have been approved by Wayne Calloway, then CEO of PepsiCo
and director of the multinationals Citicorp, General Electric and Exxon.
In 1983 soda bottlers, organized around Pepsi had petitioned the FDA for
a delay in approval of NutraSweet for soft drinks until further evaluation
verified its safety-interpreted by market analysts as a ploy to drive down
the price of the sweetener. They soon abandoned the effort to block approval
(and all health concerns they might have had). "We believe saccharine is
safe," Pepsi USA President Roger Enrico lied, but "we wanted the taste
improvement." PepsiCo, already drawing on a tenth of Searle's 7.5 million
pound annual production of aspartame, signed an agreement with G.D. Searle
to boost purchases 500 percent.89 (Like other corporate pushers of aspartame,
Pepsi has long maintained ties to the intelligence
community. One product of the relationship was a Pepsi plant in Vientiane,
Laos with a laboratory outfitted for heroin production. Alfred McCoy, in
*The Politics of Heroin in Southeast Asia* documents the efforts of Richard
Nixon to promote the plant's construction in 1965, and the CIA's continuing
subsidization of the plant. McCoy complained to Pepsi officials that the
facilities were but a cover for the importation and refinement of morphine,
but it continued to operate unhindered.)
Yet
another report was filed by Reagan's General Accounting Office in July
1987, this one on the FDA's handling of aspartame. The GAO concluded that
the agency had followed proper procedures and conducted valid studies.
But the report noted that the FDA had followed guidelines for food -not
drug- testing, despite the recommendation of the agency's own biologists
favoring *drug* tests, which are considerably more stringent. This recommendation
was overruled by FDA officials.90
Another
blemish in the study was bared by Dr. Louis Elsas, director of medical
genetics at Emory University in Atlanta. "They never asked the right questions
about what it does to brain function in humans," he told the _Washington
Post_. Half of the scientists polled expressed reservations about the safety
of NutraSweet. One-fifth reported "major concerns." Monsanto quibbled in
a press release that these critics had themselves never conducted aspartame
research. A score of independent scientists have. They found side effects.
Senator
Metzenbaum berated Searle's flawed and fabricated tests at the August 1,
1985 Senate hearings. "The FDA," he said, "is content to have the manufacturer
of aspartame, G.D. Searle, conduct these studies. How *absurd*."
He
also faulted the AMA:
The
_Journal of the American Medical Association_ recently published a report
on aspartame which, with some significant disclaimers, stated it was safe
for most people. I wish that this report could ease my concerns. It does
not. It merely restates the FDA position which relies solely on the tests
conducted by G.D. Searle. As I have indicated these tests are under a cloud.
In addition, the concerns raised recently by the scientists ... were not
even included in the report.
In
defense of the tests, executives of G.D. Searle argued that the sweetener
has been approved by foreign regulatory agencies and the World Health Organization.
But H.J. Roberts, an internal medicine specialist in West Palm Beach, Florida,
reviewed the foreign studies and found that "the vast majority of these
agencies accepted company-sponsored research without ever having done independent
confirmatory studies.''91
Deficiencies
in testing were aggravated by a lack of laboratory training at Searle.
One of the pivotal safety studies involved fetal damage, but the FDA task
force found that the medical researcher in charge was "inexperienced in
conducting studies of this nature and yet given full responsibility." They
were appalled to discover that his sole credential was a field study of
the cottontail rabbit for the Illinois Wildlife Service, yet at Searle
he'd been assigned to laboratory training and supervision. When asked about
his *curriculum vitae* in fetal research, he replied that he'd once attended
a seminar on the subject, and the company had provided him with a stack
of reference works.92 (Yet J.D. Searle, in its 1981 Annual Report, billed
itself as "a research based pharmaceutical company.")
Corporate
control of NutraSweet testing continues at Monsanto, torturing the ethics
of academic medicine. In August 1987 the University of Illinois, a recipient
of Monsanto's largess, issued a study exonerating aspartame of causing
seizures in laboratory animals. Dave Hattan, a safety regulator for the
FDA, responded that the study only confirmed the need for testing on humans.
At independent labs, he insisted, aspartame provoked seizures.
Industrial
support tends to contaminate test data. Dr. Elsas,
in a 1988 letter to the _New England Journal of Medicine_, advocates unbiased
review of clinical research. "The NutraSweet Co.," he said, "may have had
an interest in protocols that would find that their product had no untoward
effects." 94 Monsanto reportedly granted one NutraSweet researcher a $1.3
million honorarium.95 The same hired gun willing to manipulate lab results
will have no qualms publicly defending a tainted pharmaceutical, like the
diabetic specialist who objected that a Senate hearing on aspartame, which
called him as a witness, might arouse groundless public anxiety.96
Victims
and health activists have attempted in the courts to put a stop to the
marketing of NutraSweet, to no avail. In 1985 a coalition of consumer groups
were handed a ruling by the federal Circuit Court of Appeals for the District
of Columbia that the FDA had followed proper procedures in approving aspartame
for soft drinks. A year later the _Washington Post_ reported that the Supreme
Court again refused to consider the case "despite critics' arguments that
the product, sold under the brand name NutraSweet, may cause brain damage."97
Likewise,
the medical establishment has thrown up an impenetrable wall to aspartame
critics. Dr. Roberts, author of a brief study, "Aspartame-Associated Confusion
and Memory Loss: A Possible Human Model for Early Alzheimer's Disease,"
found it impossible to publish the article in a peer review medical journal.
This was peculiar, he thought, "considering the increasing magnitude of
Alzheimer's disease, and the relevance of my observations to newer biochemical
findings and avenues of research." He can "personally vouch for the *enormous*
difficulty in getting published articles concerning reactions to aspartame
products," a trend in censorship with "ominous overtones." The options,
Dr. Roberts says, are "generally limited to 'burying' the findings in a
small-circulation journal (such as the bulletin of a county medical society),
reporting the results as a letter to the editor, or (unfortunately, most
often) discarding the project."98
Silence
surrounds the most odious conspiracies.
1."Sweet
Talk," Science and the Citizen column, _Scientific American_, July, 1987,
p. 15.
2."Adverse
Effects of Aspartame-January '86 through December '90," Current Bibliography
series, National Library of Medicine pamphlet, National Institutes of Health,
U.S. Department of Health and Human Services, 1991.
3."Pepsi
Switches Sweeteners-Aspartame Winning Diet Cola Market," _Washington Post_,
November 2, 1984, p. A-1.
4.Mae
Brussell, World Watchers #842, KAZU-FM, Monterey, CA., January 25, 1988.
5._Moody
's Industrial Manual_, 1975, p 2606
6.G.D.
Searle's 1981 _Annual Report_. Also, Arnold Foster and Benjamin R. Epstein,
*Cross-Currents*, Doubleday & Co. (New York: 1956), p. 153.
7.Nancy
Lisagor and Frank Lipsius, *A Law Unto Itself: The Untold Story of the
Law Firm of Sullivan & Cromwell*, William Morrow (New York: 1988),
pp. 13738, 163.
8.John
Marks, *The Search for "The Manchurian Candidate ": The CIA and Mind Control*,
Times Books (New York: 1979), pp.58,67 & 212. Marks writes that incapacitating
"large numbers of people fell to the Army Chemical Corps, which also tested
LSD and even stronger hallucinogens. The CIA concentrated on individuals."
9.John
Peer Nugent, *White Night.- The Untold Story of What Happened Before-and
Beyond-Jonestown*, Rawson, Wade (New York: 1979), pp. 143, 177.
10.Michael
Meiers, *Was Jonestown a CIA Medical Experiment?A Review of the Evidence*,
Mellen House (Lampeter, UK: 1988) p. 42.
11.Ibid.,
p. 43.
12.Ibid.,
pp. 42-43. For a sanitized account of Dr. Layton's career, see Min S. Yee
and Thomas N. Layton, *In My Father 's House: The Story of the Layton Family
and the Reverend Jim Jones*, Holt, Rinehart and Winston (New York, 1981).
13.National
Council of the National Front of Democratic Germany and the Committee of
Anti-Fascist Resistance Fighters of the German Democratic Republic, *The
Brown Book: War and Nazi Criminals in West Germany*, Verlag Zeit im Bild,
1965, pp. 33-34.
14.Dan
J. Forrestal, *Faith, Hope & $5,000: The Story of Monsanto*, Simon
and Schuster (New York: 1977), p. 159.
15.*Brown
Book*, p. 34.
16.Tom
Bower, *The Paperclip Conspiracy: The Hunt for the Nazi Scientists*, Little,
Brown & Co. (Boston 1987), pp. 93, 95.
17.Howard
W. Ambruster, *Treason's Peace: German Dyes and American Dupes*, Beechhurst
Press (New York: 1947), p.144
18.Nigel
West, *MI6: British Secret Intelligence Service Operations, 1909-1945*,
Random House (New York: 1983), p.92
19.Jaques
Attali, *A Man of Influence: The Extraordinary Career of S. G. Warburg*,
Adler & Adler (Bethesda, Maryland: 1987),p. 167.
20.Forrestal,
p. 121ff.
21.Anthony
Cave Brown, *The Last Hero, Wild Bill Donovan*, Vintage (New York: 1982),
pp. 210211. Also: Ernst Hanfstangl, _Unheard Witness_, J.R. Lippincott
(New York: 1957)
22."Search
for the Tiger's Treasure," _Las Vegas Sun_, December 26, 1993, p.1.
23._Moody
's Industrial Manual_, 1968, p. 4080.
24."Radiation
and the Guinea Pigs," _Guardian_, March 3, 1994, p. 3. Also see, "Nuclear
Scientists Irradiated People in Secret Research," _New York Times_, December
17, 1993, p. Al.
25.Christopher
Simpson, *Blowback: America's Recruitment of Nazis and Its Effects On the
Cold War*, Wiedenfeld & Nicholson (New York: 1988), pp.26, 152-53.
Col. Pash, a former high school gym teacher, was an officer of the Office
of Policy coordination under Frank Wisner. His unit, writes Simpson, "known
as PB/7, was given a written charter that read in part that 'PB/7 will
be responsible for assassinations, kidnaping, and such other functions
as from time to time may be given it... by higher authority."' Pash was
a member of the Russian Orthodox Church, a veteran of the Russian Civil
War. Monsanto's Clinton Engineering Works in Oak Ridge became the Manhattan
Project's headquarters in 1943, and was "manned almost entirely by experienced
officers and agents of the CIC." See lan Sayer and Douglas Botting, *America's
Secret Army: The Untold Story of the Counter intelligence Corps*, Franklin
Watts (New York: 1989), pp. 71ff.,346.
26.Robin
Thomas Naylor, *Hot Money and the Politics of Debt*, Simon & Schuster
(New York, 1987), p.289.
27."Statement
from Adrian Gross, Former FDA Investigator and Scientist," _Congressional
Record_, August 1, 1985, p. S10835.
28.Florence
Graves, "How Safe is Your Diet Soft Drink?" _Common Cause_, July/August,1984.
29.Ibid.
30."FDA
Finding on Aspartame," _New York Times_, January 14,1984, p. 28.
31.Article
in Medical World News,1978, cited in I .N. Love "NutraSweet Isn't that
Sweet," _Gentle Strength Times_, October 1987, p. 3.
32."Dick
Wurtman's Ideas Aren't So Crazy After All," _Business Week_, December 14,
1992, p. 60.
33."A
Sour View of Aspartame ," _San Francisco Chronicle_, August 25, 1987.
34."Amendment
No. 60" (debate), _Congressional Record_, May 7, l985, p. S5516.
35."Lobbyist's
Cozy Ties with Ex-Boss Sen. Hatch Include Client Referrals, Political Fund-Raising,"
_Wall Street Journal_, February 18, 1993. Eli Lilly contributed $17,500
to Hatch's campaign chest between 1985 and 1988. Sen. Hatch filed a of
friend-of-the-court brief on behalf of Eli Lilly in a 1989 patent case.
Other pharmaceutical houses enjoy his political favors. Lobbyist Thomas
Parry remains a key adviser to Sen. Hatch:- "Nobody gets better care than
his former chief of staff," reports the _Journal_.
36.Ibid.
37.Jane
E. Brody, "Sweetener Worries Some Scientists," _Science Times_, February
5, 1985.
38._Who
's Who in Industry and Finance_, 97th ed., Macmillian (Wilmette, IL.) p.
583.
39."Food
and Drug Administration Food Additive Approval Process Followed for Aspartame,"
GAO Report B223552, June 18,1987.
40."GAO
Investigating NutraSweet Approval," UPI, reprinted in _Congressional Record_,
August 1, 1985,p. S10823.
41.Graves.
42."Head
of FDA Tested Drugs on Volunteers," _Washington Post_, June 26, 1983, p.
A4.
43.Austin
H. Kiplinger, *Washington Now*, Harper & Row (New York: 1975), pp.
36-37.
44.Daniel
Guttman and Barry Willner, *The Shadow Government: The Government's Multimillion
Dollar Giveaway of its Decision-Making Powers to Private Management Consultants,
''Experts, " and Think Tanks*, Pantheon, (New York:1989),p.173.
45.Bruce
Oudes, ed., *From: The President-Richard Nixon 's Secret Files*, Harper
& Row (New York: 1989), p. 173.
46.James
A Smith, *The Idea Brokers: Think Tanks and the Rise of the New Policy
Elite*, Free Press (New York: 1991), p.282.
47.Sterling
Seagrave, *Yellow Rain: A Journey Through The Terror of Chemical Warfare*,
M. Evans and Co. (New York: 1981), pp. 258 "After a meeting with President
Nixon, Representative Gerald Ford attacks politicians who criticize the
Pentagon CBW efforts, saying the critics seem to favor 'unilateral disarmament."'
48.Christopher
Palmeri, "Act Three," _Forbes_, October 26, 1992, p. 88
49."Westmark
Systems Expands Board, Hires 3 New Vice Presidents," _Wall Street Journal_,
February 11,1988, p.33.
50.Graves.
51.Ibid.
52."Hon.
Samuel K. Skinner," _Congressional Record_, Congressional Printing Office,
Washington, D.C., August 1, 1985, pp. S10827, S10835.
53.Graves.
54._Congressional
Record_, August 1,1985, p. S10823.
55.Graves.
56."Critics
Cause Bush Cabinet Search to Stumble," _Los Angeles Times_, December 22,1988.
57.Herman
Rogan, *Traditions and Challenges: The Story of Sidley & Austin*, R.R.
Donelly & Sons (Chicago: 1983), p.266.
58.*Who's
Who in America*, 48th ed., 1994.
59.Ibid.
60."Deukmejian
Thrives in Private Life, Law Work," _Los Angeles Times_, January 3, 1992,
p. Al.
61."Chicago
Law Firm Agrees to Pay Up to $34 Million in Lincoln S&L Case," _Los
Angeles Times_, May 21, 1991, p. D5;and "Sidley & Austin RTC Said to
Reach Pact," _Wall Street Journal_, October 31, 1991, p. B4. The basis
of the suit was a memo written on May 10, 1988 by Margery Waxman, a partner
in Sidley & Austin's Washington office, to Charles Keating. In it,
she said "pressure" had been applied to M. Danny Wall, then chairman of
the Home Loan Bank Board, "to work toward meeting your demands and he has
so instructed his staff."
62."Suit
Accuses 7 Drug Makers of Price-Fixing," _Los Angeles Times_, October 15,
1993, p. Dl. Other pharmaceutical houses accused of conspiring to fix prescription
drug prices included Smith-Kline-Beecham, Ciba-Geigy Corp., American Home
Products, Schering-Plough and Glaxo.
63.Ida
Honorof, "FDA Coverup of Hazards of Nutra-Sweet," _Report to Consumers_,
Vol. XVIII, No.401, December, 1987. Also, "Two Ex-U.S. Prosecutors' Roles
in Case Against Searle are Questioned in Probe," _Wall Street Journal_,
February 7,1986, p. 4. Ironically, William Conlon won an appointment to
the Illinois State Board of Ethics in 1982 (Kogan, p.359).
64.Graves
65._Los
Angeles Times_, December 22, 1988.
66."Sam
Skinner: A Pragmatist in a Storm," _Wall Street Journal_, December 6, 1991.
67."Samuel
Knox Skinner," _New York Times_, December 23, 1988.
68.Graves.
69."Statement
from Adrian Gross, Former FDA Investigator and Scientist," _Congressional
Record_, August 1, 1985, p. S10835.
70._Congressional
Record_, August 1, 1985, p. S 10831, and "Statements from Adrian Gross,"
p. S10838.
71."FDA
Handling of Research on NutraSweet is Defended," _New York Times_, July
18, 1987, p. 50
72.H.J.
Roberts, M.D.,*Aspartame (NutraSweet): Is it Safe?*, Charles Press (Philadelphia:
1990), p. 10.
73._Congressional
Record_, August 1, 1985, p. S108-28.
74.Ibid.,
p. S108-34.
75.Ibid.
76.Graves.
77."Sweet
Suspicions," three-part CBS Nightly News series, January 1984. Transcript
reprinted in the _Congressional Record_, August 1, 1985, p. S108-26.
78.Ibid.
79.Raymond
Bonner, "Searle Stock Query Held 'Smokescreen,"' _New York Times_, February
29, 1984, p. D5
80.William
Safire, "Sweet and Sour," _New York Times_, June 1, 1984, p. A31.
81.Louis
Wolf, "Accuracy in Media Rewrites the News and History," _Covert Action
Information Bulletin_, Number 21 (Spring 1984), pp. 24-37.
82.I.N.
Love, "NutraSweet Isn't that 'Sweet,"' in _Gentle Strength Times_, October
1987, p.3.
83.Graves.
84."Complaints
on Aspartame Lead to Nationwide Investigation," _Los Angeles Times_, July
5, 1984, p. Hl.
85."Federal
Agency Sees Little Risk in Sweetener," _New York Times_, November 2, 1984,
p. A22.
86._Los
Angeles Times_, July 5, 1984.
87._New
York Times_, November 2, 1984.
88."U.S.
Study of Aspartame Finds no Serious Effects," _Washington Post_, November
2, 1984, p. A18
89."Pepsi
Switches Sweeteners," _Washington Post_, November 2, 1984, p. AI.
90."Most
Scientists in Poll Doubt NutraSweet's Safety," _Washington Post_, August
17, 1987, p. A23.
91.Roberts,
p. 238.
92._Congressional
Report_, May 7, 1987, p. S5500.
93."New
Findings Back Use of Sweetener," _New York Times_, August 1987, p. 30.
94."Researchers
Differ Over Long Range Effects of Sweetener," _Los Angeles Times_, November
3, 1988, p. Hl.
95.Roberts,
p. 244.
96.Roberts,
p. 248.
97."High
Court Rejects Sweetener Review," _Washington Post_, April 23, 1986, p.
C.
98..
Roberts,p. 246-47. |